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diagnosis differential lfts transaminitis aclf acute autoimmune chemistry cirrhosis dili druginduced failure function gastroenterology hepatocellular interpretation management rvalue tests
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
Tests (LFTs) - ... Cirrhosis • Chronic ... Viral Hepatitis ... injury) • Ischemic ... Differential #Diagnosis #hepatology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... Circulation Failure Kidney ... Injury (DILI) ... Viral Hepatitis ... #Cirrhosis #Hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Stepwise Diagnosis Algorithm ... Skin involvement, Kidney ... e.g. ascites), Chronic ... hepatitis fibrosis ... #Algorithm #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Acute Liver Injury ... Differential Diagnosis Algorithm ... extrahepatic source - Tests ... #injury #hepatitis ... #hepatology
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
Injury → liver ... test abnormalities ... #Diagnosis #hepatology ... #algorithm #Transaminitis ... #LFTs #hepatitis
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Check Acute viral hepatitis ... > 2 • NASH, Chronic ... viral hepatitis ... : > 3 • Chronic ... #differential #Hepatology
Autoimmune Hepatitis - Testing Algorithm Individual Tests: • F-Actin (Smooth Muscle) Antibody, IgG by ELISA with Reflex
Autoimmune Hepatitis ... Individual Tests ... IgG by IFA • Liver ... /Kidney Microsome ... #hepatology
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