43 results
Pathophysiology of Diabetic Ketoacidosis (DKA) and Hyperglycemic Hyperosmolar Syndrome (HHS)
Absolute Insulin deficit:
 - Type I DM:
Pathophysiology of Diabetic ... Ketoacidosis (DKA ... pts under large stresses ... TX, stresses ↑ ... Polydipsia #dka
Pathogenesis of Diabetic Ketoacidosis - Insulin deficiency or severe insulin insensitivity 

#DKA #Pathophysiology #Endocrinology #Diabetes #Ketoacidosis
Pathogenesis of Diabetic ... Ketoacidosis - Insulin ... deficiency or severe insulin ... insensitivity #DKA ... Endocrinology #Diabetes
Pathophysiology and Effects of Insulin Deficiency

#Insulin #Deficiency #DKA #Ketoacidosis #Diabetes #Pathophysiology #Endocrinology
and Effects of Insulin ... Deficiency #Insulin ... #Deficiency #DKA ... #Ketoacidosis #Diabetes
Pathogenesis and Pathophysiology of Diabetic Ketoacidosis (DKA)

DKA is a result of an absolute or relative insulin
Pathophysiology of Diabetic ... Ketoacidosis (DKA ... ) DKA is a result ... Pathophysiology #Diabetic ... #Diabetes #Endocrinology
DKA DIAGNOSTIC CRITERIA:
1. Serum glucose >250 mg/dL
2. Arterial pH <7.3
3. Serum bicarbonate <18 mEq/L
4. At least
DKA DIAGNOSTIC CRITERIA ... have new-onset diabetes ... Continue insulin ... and subcutaneous insulin ... #DKA #EDKA #Insulin
DKA vs HHS
 - Think of DKA and HHS on a spectrum of hyperglycemic emergencies
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of DKA and HHS ... emergencies - HHS = insulin ... restart any home insulin ... comparison #laboratory #diagnosis ... endocrinology #comparison #diabetic
"Eight I's" mnemonic for the main causes of hyperglycemia. #hhs #dka #ketoacidosis #diabetes #diabetic #em #differential
#hhs #dka #ketoacidosis ... #diabetes #diabetic ... #differential #diagnosis
Ketosis Disorders - Comparison Table
 • Starvation Ketosis
 • Alcoholic Ketoacidosis (AKA)
 • Diabetic Ketoacidosis (DKA)
) • Diabetic Ketoacidosis ... (DKA) • Euglycemic ... DKA • Hyperglycemic ... State (HHS) • DKA ... #differential #diagnosis
Ketosis Disorders
Ketone bodies are a normal metabolic energy source. Excessive unregulated production of ketones, often accompanied
produce endogenous insulin ... • Diabetic ketoacidosis ... by complete insulin ... HHS) - partial insulin ... #differential #diagnosis
SGLT2 Inhibitors and Euglycemic DKA

Risk factors for euglycemic DKA in those on an SGLT2i include:
 •
• Increased insulin ... and surgery) • Insulin ... alcohol consumption Diagnostic ... Consideration of insulin ... SGLT2 #Euglycemic #DKA