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diagnosis differential hepatology management transaminitis hematology product reactions acidosis algorithm arthritis causes chemistry classification disease elevation function hepatitis hepatitisb hepbv
Hepatitis B - Treatment Indications Treatment not indicated: • Immune tolerant state - HBe-Ag detectable, high HBV
Family history of cirrhosis ... or fibrosis • Cirrhosis ... severe liver injury ... > 3 mg/dL) or acute ... liver failure
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
Tests (LFTs) - ... • NAFLD • Cirrhosis ... Hepatopathy • Acute ... injury) • Ischemic ... Function #Tests #LFTs
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Acute Liver Injury ... Liver Injury: ... Liver Injury: ... hepatitis: < 1 • Cirrhosis ... intestines, white blood
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
Patterns of Liver ... > 20x normal - Acute ... normal - Infection (EBV ... CMV), Alcoholic cirrhosis ... #LFTs #transaminitis
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Interpretation of LFTs ... hepatitis serologies, HCV ... hepatitis: < 1 • Cirrhosis ... intestines, White blood ... transaminitis #LFTs
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
- Acute Hemolytic ... Transfusion Related Acute ... Lung Injury (TRALI ... eruptions, diarrhea, liver ... 2,000,000,000, HBV
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
• Acute Hemolytic ... Transfusion Related Acute ... Lung Injury (TRALI ... eruptions, diarrhea, liver ... 2,000,000,000, HBV
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
removal from the blood ... or renal injury ... cardiac output - Acute ... peritonitis - Acute ... Injury: • Reduced
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Screening Tests for Acute ... Polyarthritis: • Blood ... : • Complete blood ... profile, including liver ... function tests (LFTs
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