10 results
Clinical Classification of Pulmonary Hypertension

1. Pulmonary arterial hypertension from pulmonary vasculopathy
Idiopathic pulmonary arterial hypertension
Heritable gene mutations
Clinical Classification ... Pulmonary arterial ... diseases - HIV ... Hypertension #PHTN #Classification ... #Differential #Causes
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
Causes of Bone/Joint ... predispose to other orthopedic ... common sites: hip ... differential #diagnosis #causes ... #hematology
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
Pathophysiology: 2 hit ... without other cause ... , and CXR with pulmonary ... Transfusion #Reactions #hematology
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
Causes of Lactate ... The most common causes ... output - Acute pulmonary ... Ethylene glycol - HIV ... #typea #typeb #classification
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Cryoglobulins Cause ... HBV infection, HIV ... diagnosis #types #classification ... #rheumatology #
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
thrombophlebitis, pulmonary ... cryoglobulins • Negative causes ... • TTP, HUS and HIT ... Cryofibrinogenemia #diagnosis #rheumatology ... #hematology
Nontuberculous Mycobacteria (NTM) Infections 

Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
status NTM Cause ... Growers (Runyon Classification ... Growers (Runyon Classification ... mucogenicum • HIV ... Advanced HIV (CD4
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
progressing GN • New pulmonary ... tract, and often causes ... Cryoglobulins • HIV ... differential #diagnosis #rheumatology ... #classification
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Hypocomplementemia • Can cause ... Xerostomia • Dental caries ... Disease: • 10%-15% Pulmonary ... , INC risk PE, Pulmonary ... Sjogrens #Syndrome #Rheumatology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
progressing GN • New pulmonary ... of shoulder and hip ... MPO > PR3) • Pulmonary ... tract, and often causes ... Differential #Diagnosis #Rheumatology