9 results
Bone Deformity / Limp - Differential Diagnosis Algorithm 
Infection
 • Septic Arthritis
 • Cortical Hypertrophy
 •
Bone Deformity / ... Limp - Differential ... Patellofemoral Syndrome ... #MSK #Differential ... #Orthopedics #Causes
Vascular Joint Pain - Differential Diagnosis Algorithm 
 - Constant Pain (Ischemia)
 - Acute Onset
 -
• Sickle Cell Anemia ... fractured long bone ... Marfan's Syndrome ... Vascular #JointPain #MSK ... #Orthopedics #Causes
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Clinical Presentation ... and petechiae Causes ... - HCV - HIV ... CMV) • Epstein-Barr ... hematology #diagnosis #management
Mallet Finger
Absence of a fracture does NOT exclude Mallet finger, the extension function of the DIP
joint needs to be clinically ... Finger deformity caused ... disruption (may be bony ... #Hand #Orthopedics ... #MSK
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Guillain-Barré Syndrome ... Incidence: 1 to 2 cases ... surgery, trauma, and bone-marrow ... transplantation CLINICAL ... #management #neurology
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to 8 years Clinical ... autoimmune hemolytic anemia ... DDX - Other causes ... infections (Epstein-Barr ... syndrome, HIV)
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary

Epidemiology:
 • Prevalence: 1-2 cases per million -
Diagnosis and Management ... Prevalence: 1-2 cases ... and pernicious anemia ... Clinical Manifestations ... dystonia, Focal limb
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Anti-La/SSB ab • Lip ... Diagnosis: • LIP ... salivary ducts Clinical ... Interstitial Pneumonitis (LIP ... phenomenon (16%) MSK
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
Reconstitution Inflammatory Syndrome ... noncompliance • Clinical ... initiation Clinical ... albicans • Epstein Barr ... Differential #Diagnosis #Management