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diagnosis hematology 21hydroxylasedeficiency 21ohd algorithm bullous causes differential endocrinology genetics hemeonc hemophagocytic hlh leukostasis lymphohistiocytosis lysis papulosquamous pediatrics peds pemphigoid
Papulosquamous Skin Rash - Differential Diagnosis Algorithm Erythrematous or violaceous papules & plaques with overlying scale •
Auspitz sign, Koebner's ... genitals (especially penis ... Rosea - Oval, tannish-pink ... Papulosquamous #SkinRash #dermatology
Reactive Arthritis • Inflammation of joints (commonly large joints) - Asymmetric Oligoarthritis: Joint
pustules of the glans penis ... ReactiveArthritis #pathophysiology ... #diagnosis #signs
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
Signs/Symptoms/Complications ... scrotum & enlarged penis ... may look like a penis ... #21HydroxylaseDeficiency #21OHD #pathophysiology
Bullous Pemphigoid - Diagnosis and Management Summary Pathophysiology: Autoantibody-mediated damage to epithelial basement membrane -> separation of
Diagnosis and Management ... Summary Pathophysiology ... dermis Clinical Signs ... erosions in ~20% Management ... #dermatology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... WBC >100k, + lab signs ... Lysis Syndrome: • Pathophysiology ... TLS #diagnosis #management ... #hematology
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
recognition and management ... Presentation • Common Signs ... Pathophysiology ... Approach • Initial management ... #Hematology #HemeOnc
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