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diagnosis rheumatology ana antinuclear classification pulmonary vasculitis autoimmune cystic dcld disease disorders glomerulonephritis hematology lung lymphomas lymphoproliferative management myopathy myositis
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
ANA Patterns and ... Associated Rheumatic ... • Nucleolar: Diffuse ... #Antinuclear #Antibodies ... rheumatology #diagnosis #differential
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... are associated ... and Associated ... • Nucleolar: Diffuse ... rheumatology #diagnosis #differential
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
Rapidly Progressive ... Purpura Anti-GBM antibodies ... Glomerulonephritis • With associated ... Glomerulonephritis #Vasculitis #differential ... #diagnosis #algorithm
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Diagnosis Algorithm ... system (node) with progression ... lymphadenopathy more diffuse ... involvement, irregular pattern ... #algorithm
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
EGPA) • Auto-antibodies ... capillaritis leading to diffuse ... hemorrhage (DAH) • Diffuse ... Path: rapidly progressive ... • IF staining patterns
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Vasculitides - Differential ... proteinuria, rapidly progressing ... - (C-ANCA) pattern ... : antibodies directed ... - (P-ANCA) pattern
Algorithm for Diagnosis of Diffuse Cystic Lung Disease (DCLD) Round, smooth cysts with normal lung parenchyma in
Algorithm for Diagnosis ... May have associated ... LCDD, SS Cyst pattern ... DCLD #pulmonary #Algorithm ... #Diagnosis #differential
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Autoimmune Myositis - Differential ... Anti-TIF1 (cancer-associated ... POLYMYOSITIS: • Progressive ... slow onset and pattern ... #rheumatology #differential
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