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diagnosis treatment differential hematology types reactions shock allergy anesthesia anesthesiology cardiology checklist criticalcare intraoperative neurology oncology workup blood encephalopathy hemophagocytic
Summary table of types of hypersensitivity reactions. Type 1 - Mediators: lgE - Antigen Form: Soluble
Allergen-specific lgE causes ... mast-cell degranulation ... antigens, leading ... T-cells recruit ... allergy #table #classification
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Activation of CD8 T cells ... , Hb), Hepatic dysfunction ... lymphoma, B-cell ... Drugs, Unknown cause ... Lymphohistiocytosis #diagnosis #management
Clinical Classification of Pulmonary Hypertension 1. Pulmonary arterial hypertension from pulmonary vasculopathy Idiopathic pulmonary arterial hypertension Heritable gene mutations
Clinical Classification ... disease Systolic dysfunction ... Diastolic dysfunction ... pulmonary Langerhans cell ... #Differential #Causes
Angioedema - Classification Diagnosis and Treatment Types of Angioedema: • Acute allergic angioedema - Usually occurs with
Angioedema - Classification ... in > 90% of cases ... is key • Mast cell-mediated ... #Angioedema #Classification ... Diagnosis #Treatment #management
Shock Overview A state of tissue hypoxia due to decreased or dysregulated oxygen delivery or extraction, resulting
rapidly progresses: cell ... death -> end-organ dysfunction ... #diagnosis #management ... #differential #causes ... #classification
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Diagnosis and Management ... dysfunction and ... increased B-cell ... symptoms are not caused ... Sarcoidosis #Diagnosis #Management
Shock Overview A state of tissue hypoxia due to decreased or dysregulated oxygen delivery or extraction, resulting
rapidly progresses: cell ... death -> end-organ dysfunction ... #diagnosis #management ... #differential #causes ... #classification
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
64%) • Renal dysfunction ... Schistocytes, helmet cells ... Treat primary cause ... Coagulation #diagnosis #causes ... #treatment #management
Intraoperative Sepsis - Guidelines for Crises in Anaesthesia Severe sepsis (hypotension persisting after initial fluid challenge of
likely underlying cause ... with end organ dysfunction ... ). ❶ Call for ... devices could have caused ... Discuss ongoing management
Diabetic Foot: Pathogenesis and clinical findings • Polyol Pathway - Excess glucose enters Polyol pathway ->
accumulates in cells ... essential for cell ... Glycosylation - AGE cause ... increasing cytogenetic dysfunction ... in inopportune loading
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