8 results
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... Diagnosis via genetic ... lymph node, or liver ... #management #treatment ... #hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Assessment • Clinical ... of emergency, ICU ... #management #treatment ... #summary #rheumatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
lymphohistiocytosis (HLH ... Fever is the main clinical ... thrombocytopenia • Liver ... Activation #Syndrome #Diagnosis ... #Management #Hematology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Antithrombin Ill • Ultrasound ... ) Differential Diagnosis ... Maternal Support - Critical ... #Pregnancy #hepatology ... obstetrics #obgyn #diagnosis
Pain, Agitation, and Delirium (PAD) in the ICU
Addressing the ICU Triad (PAD) can be accomplished through
Family engagement Critical ... will vary with clinical ... bradycardia. renal/liver ... #CriticalCare # ... diagnosis #management
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to 8 years Clinical ... disease • Liver ... Lifelong IV or subcutaneous ... hypogammaglobulinemia #immunology #hematology ... #diagnosis #management
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
organ damage Clinical ... fulminans • Subcutaneous ... DIC • Severe Liver ... #Coagulation #diagnosis ... #hematology
It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
diagnosis but rather ... importantly, bedside ultrasound ... #algorithm #management ... heartfailure #chf #criticalcare ... #icu #clinical