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diagnosis management treatment causes latenttb tb tuberculosis antibiotic betadglucan brain cns failure falsepositives fever fungal galactomannan immune infections inflammatory intermittent
Lung Abscess - Diagnosis and Management Summary Lung Abscess Etiology: • Necrosis of lung parenchyma by a
Lung Abscess - Diagnosis ... Lung abscess ... : • Aerobic Bacteria ... Abscess Differential ... #differential #
CNS Ring-Enhancing Lesions - Immunocompromised vs Immunocompetent Multiple Ring-Enhancing Lesions: • Toxoplasmosis (CD4 < 100) • Other
toxo IgG • CNS PCR ... lesions • 80% with lung ... Infectious: • Bacterial ... Syphilis • Pyogenic Abscess ... Lesions #Brain #differential
Tuberculosis Overview 10 million new M. tuberculosis infections/year Facultative intracellular rod-shaped bacteria Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
intracellular rod-shaped bacteria ... affecting the lungs ... abscess Primary ... Response: • Most bacteria ... staining, NAA (PCR
Fever Patterns - Differential Diagnosis Framework Continuous Fever: Temp > 38°C with only 1 degree fluctuation in 24
Fever Patterns - Differential ... infection • Abscess ... Leptospirosis Pel-Ebstein ... Brucellosis • Liver or lung ... Fever #Patterns #Differential
Tuberculosis Overview 10 million new M. tuberculosis infections/year Facultative intracellular rod-shaped bacteria Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
intracellular rod-shaped bacteria ... affecting the lungs ... abscess Primary ... Response: • Most bacteria ... staining, NAA (PCR
Causes of Antibiotic Failure - Differential Diagnosis Framework Diagnosis: • Non-Infectious: Malignant, Autoimmune, Drug-related (NMS, serotonin syndrome,
Antibiotic Failure - Differential ... Bug: Atypical bacteria ... Source control (abscess ... ocular), Tissue activity ... (daptomycin in lungs
1,3-Beta-D-Glucan and Galactomannan Testing Sensitivity Specificity and False Positives 1,3-Beta-D-Glucan • Cell wall component of many fungi
Other +s: PCP, Histo ... Infections with certain bacteria ... in BAL does not differentiate ... concurrent admin mold-active ... result in + as long
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
drug-resistant infection, bacterial ... osteomyelitis, cutaneous abscesses ... leukoencephalopathy (PML ... Leishmaniasis Differential ... • Persistently active
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