7 results
Causes of blood culture negative infective endocarditis

Bartonella spp, Brucella spp, Coxiella burnetii, Chlamydia spp, Tropheryma whipplei,
culture negative ... identified with modern culture ... #Causes #differential ... #culture #negative ... #BCNIE #cardiology
Blood Culture-Negative Infective Endocarditis (BCNIE)
Definition: No etiology found after 3 separate blood cultures remain negative for
Blood Culture-Negative ... but important causes ... identified with modern culture ... - Standard culture ... #diagnosis #differential
Primary and Secondary Causes of Mitral Regurgitation
Primary (organic) chronic mitral regurgitation:
 • Leaflet: Rheumatic fever, Infective
), Spontaneous rupture ... infarction, Tendineae rupture ... Papillary muscle rupture ... Regurgitation #differential ... #diagnosis #cardiology
Endocarditis Summary

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV substance use
• IV catheter
• Recent
Involves aortic and mitral ... Culture (+): ... • Coagulase-negative ... staphylococci Culture ... #cardiology
Causes of Primary and Functional Mitral Regurgitation (MR) 
Causes of primary mitral regurgitation
 - Rheumatic heart
Infective/marantic endocarditis ... MV chordae may rupture ... laterally from myocardial ... #Functional #Differential ... #Diagnosis #Cardiology
Endocarditis - Overview and Differential Diagnosis Framework

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV
involves aortic and mitral ... Culture Positive ... staphylococci Culture ... Diagnosis #cardiology ... #infectiousdiseases
CNS Infections - Viral Encephalitis and Bacterial Meningitis - Differential Diagnosis Framework

Viral Encephalitis:
MCC: Enteroviruses (e.g., coxsackievirus
in 60%-90% • Culture ... in 70%-85% • Negative ... Monocytogenes or gram negative ... by CSF or urine culture ... #diagnosis #neurology