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diagnosis betadglucan causes dermatology fungal galactomannan nephrology rash acute aspergillus bacteremia biomarkers chloride color comparison ddxof erythematous falsepositives febrile hypochloremia
Fever - Pyrogen Pathophysiology EXOGENOUS PYROGEN • Bacteria: Lipopolysaccharide components, peptidoglycans and muramyl peptide derivatives, Toxins •
Pathophysiology ... macrophages) → Synthesis ... vasculature via: • Active ... Pyrogen → Induce synthesis ... #Fever #Pathophysiology
Erythematous Rashes - THE ALGORITHMIC APPROACH Characterized by diffuse redness of the skin due to capillary congestion, erythematous
Erythematous Rashes - THE ALGORITHMIC ... Nikolsky sign, the differential ... or an exposure reaction ... Erythematous #Rash #Algorithm ... #Differential
Maculopapular - Diagnostic Algorithm Pathophysiology: - Catch-all term with a wide range of potential pathophysiologic mechanisms and causative
Maculopapular - Diagnostic Algorithm ... Pathophysiology ... instability - New-onset fever ... Color #Targetoid #Algorithm ... #Differential #
Causes of Acute Onset Fever - Differential Diagnosis Algorithm Viral: • Rhinovirus • Influenza Virus • Parainfluenza
- Differential ... Diagnosis Algorithm ... • Transfusion reaction ... #Differential # ... Diagnosis #Algorithm
Rigors And Bacteremia - Overview • Rigors are a response to the release of cytokines and prostaglandins
hypothalamus → fever ... PATHOPHYSIOLOGY: ... Macrophages → Synthesis ... vasculature via: • Active ... pyrogen induces synthesis
Causes of Proteinuria - Differential Diagnosis Algorithm Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
Proteinuria - Differential ... Diagnosis Algorithm ... • Exercise • Fever ... albuminuria) - Active ... #Diagnosis #Algorithm
Hypochloremia - Differential Diagnosis Algorithm Cause - Decreased Intake: • Low salt in diet • Exclusive D5W
Hypochloremia - Differential ... Diagnosis Algorithm ... Hypochloremia #Differential ... #Diagnosis #Algorithm ... #Pathophysiology
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan Beta-D-Glucan: • Polysaccharide cell wall component of many fungi • Pathogens:
dialyzer membranes synthetic ... BAL GM does not differentiate ... admin of mold-active ... post-2010 almost never
1,3-Beta-D-Glucan and Galactomannan Testing Sensitivity Specificity and False Positives 1,3-Beta-D-Glucan • Cell wall component of many fungi
dialyzer membranes synthetic ... in BAL does not differentiate ... concurrent admin mold-active ... post-2010 almost never
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