1151 results
Functions of the Liver

Storage 
Degradation 
Metabolism 
Synthesis 

#Pathophysiology #Functions #Liver #Hepatology #Synthesis #Storage #Metabolism
Degradation Metabolism ... Synthesis ... #Pathophysiology ... Liver #Hepatology #Synthesis ... #Storage #Metabolism
Steroid Synthesis Pathway

(OH, hydroxy; HSD, hydroxysteroid dehydrogenase; DHEA, dehydroepiandrosterone; pink, common enzymes affecting CAH, purple –
Steroid Synthesis ... CaoimheCostigan #Steroid #Synthesis ... #Pathway #metabolism ... #pathophysiology
Synthesis, metabolism and functions of vitamin D. PTH parathyroid hormone, FGF-23 fibroblast growth factor-23, RANKL receptor
Synthesis, metabolism ... ligand #VitaminD #Metabolism ... #Pathophysiology
Vitamin D Metabolism
Fat-soluble vitamin
Sources: dermal synthesis and food (dairy products, fish)
Active form: calcitriol (1,25-OH Vitamin D)
Main
Vitamin D Metabolism ... Sources: dermal synthesis ... mendesthiagob #VitaminD #Metabolism ... endocrinology #pathophysiology
Liver Chemistry Tests - AST, ALT, Alkaline Phosphatase and Bilirubin Metabolism
AST and ALT:
 • AST: liver
and Bilirubin Metabolism ... phosphatase: • Synthesis ... due to increased synthesis ... clearance - AP synthesis ... Bilirubin #Hepatology #Pathophysiology
Lipoprotein Metabolism

Enterocytes release absorbed lipids the form of triglyceride-rich chylomicrons. These are acted upon by endothelial
Lipoprotein Metabolism ... cholesterol to synthesize ... #Cholesterol #Metabolism ... #Pathophysiology
Refeeding Syndrome: Pathogenesis and clinical findings

Patients at Risk of Refeeding Syndrome:
 - Little or no nutritional
• Incr Glucose Metabolism ... Syndrome - Metabolic ... Death • Incr synthesis ... Syndrome #diagnosis #pathophysiology
Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
expression/protein synthesis ... thickness) - metabolic ... endocrinology #pathophysiology
Rickets and Osteomalacia: Pathogenesis and Clinical Findings
 • Calcification inhibitors (excess exposure to A1, Fluoride, etidronate)
Abnormal Vitamin D Metabolism ... hereditary disorders of synthesis ... #Osteomalacia #pathophysiology
A schema of the pathophysiology of the inborn errors of metabolism, excluding complex storage diseases. Helps
schema of the pathophysiology ... inborn errors of metabolism ... connections and pathophysiology ... presentations in acute metabolic ... #Pediatrics #Metabolism