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Syphilis - Clinical Manifestations and Treatment

1) Primary Syphilis
 • Direct lesion contact during sex is responsible
loss • Skin: Rash ... Albuminuria, nephrotic syndrome ... meningovascular disease ... ulcerated • MSK ... Coronary artery disease
Infectious Joint Pain - Differential Diagnosis Algorithm 
Polyarticular Join Pain
 • Viral Myalgia
 • Viral Arthritis
• Secondary Syphilis ... Lesions) • Fifth Disease ... & Symmetrical Rash ... (Measles- like rash ... #JointPain #MSK
Natural History of Syphilis
Primary - 2-6 weeks after infection
 • Chancre, Regional lymphadenopathy
Early Latent ≤ 1
-6 weeks after infection ... ≤ 1 year after infection ... • Rash, Fever ... • Gummatous disease ... Meningovascular disease
Secondary Syphilis Rash
Secondary syphilis is the most contagious of all the stages of this disease, and
stages of this disease ... with or without treatment ... , but without treatment ... , the infection ... late stages of disease
Fever and Rash - Differential Diagnosis Framework
 • Viral: Measles, Infectious Mono (EBV, CMV), Acute HIV,
Fever and Rash - ... Viral: Measles, Infectious ... meningitis, Secondary syphilis ... gonorrhea, Rickettsial diseases ... , Toxic shock syndrome
Approach to the Rash in a an oncology patient - MINT-C Mnemonic
M - Malignancy: Leukemia cutis,
Approach to the Rash ... , Viral infections ... Dermatoses: Sweet Syndrome ... Gangrenosum, NEH T - Treatment ... dermatoses #skin #Rash
CDC Sexually Transmitted Infections (STI) Treatment Guidelines, 2021
 • Bacterial Vaginosis
 • Cervicitis
 • Chlamydial Infections
Sexually Transmitted Infections ... (STI) Treatment ... Pelvic Inflammatory Disease ... • Scabies • Syphilis ... #STI #Treatment
BEE Syndromes - Non-inflammatory Causes

Immune-mediated conditions affecting the Brain, Eye, and Ear

Visual or auditory symptoms in
and less common diseases ... diagnosis and treatment ... • Syphilis ... • Lyme disease ... consistent with MS
The Stages of Syphilis 

Primary Syphilis 
- The chancre lesion is the hallmark of primary syphilis.
Without treatment ... - Rash, pink ... and nephrotic syndrome ... to asymptomatic infection ... Diseases - https
Treatment Recommendations for Syphilis in Non-Pregnant Adults by Syphilis Stage

Incubating Infection, Primary, Secondary, Early Latent Syphilis:
Treatment Recommendations ... Incubating Infection ... disease specialist ... Testing for HIV infection ... Primary #Latent #Treatment