10 results
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
(SLE) Clinical ... Demyelinating Syndrome ... : • Inflammatory ... #SLE #CNS #neurology ... #rheumatology #
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
Symptoms: • Asymptomatic ... (COVID-19) • Inflammatory ... processes: • Systemic ... #diagnosis #rheumatology ... #hematology
Statin Induced Muscle Toxicity - Summary

Clinical Presentation:
 • Elevations of serum creatine kinase with proximal myalgia
Toxicity - Summary Clinical ... weakness without skin ... lupus erythematosus ... (SLE), polymyositis ... sclerosis.
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
Hyperostosis: Sclerotic ... out other causes ... and lower jaw Treatment ... #Rheumatology # ... #Dermatology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Systemic disease ... Disease (25-75%): Inflammatory ... Treatment: • Oral ... #signs #symptoms ... #rheumatology #
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
tract, and often causes ... aneurysms can also ... Symptoms (Sx) in ... vasculitis, and SLE ... #rheumatology #
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
Pathophysiology ... of the nervous system ... can become pro-inflammatory ... column Treatment ... #neurology #diagnosis
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
SLE, atherosclerotic ... , particularly scleritis ... purpura: Strong sign ... : Erythematous nodules ... #Rheumatology
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
inflammatory vasculitis ... Diagnosis = clinical ... required due to skip ... them, but urgent rheumatology ... #Symptoms #Diagnosis
Relapsing Polychondritis

What is it?
Recurrent inflammation of the cartilage in the body (Autoimmune disorder)

Who?
• Most frequently: 40
keratitis, uveitis, scleritis ... • Inner ear • Skin ... such as: • SLE ... affected tissue Treatment ... Polychondritis #rheumatology