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Subacute Thyroiditis

Also known as: de Quervain’s thyroiditis, granulomatous thyroiditis, or viral thyroiditis

What?
Postviral inflammatory process caused by
inflammatory process caused ... in viruses and thyroid ... after onset Causes ... phase: ↑ T4 and T3 ... levels, ↓ TSH (2) Hypothyroid
Thyroid Function Test Interpretation Table

TSH, Free T4, Free T3 and Associated Condition
#Diagnosis #Endocrinology #Hyperthyroid #Hypothyroid #Function
Thyroid Function ... Free T4, Free T3 ... Endocrinology #Hyperthyroid ... #Hypothyroid #Function
Abnormal Serum TSH - Differential Diagnosis Algorithm
Increased TSH
 • Hypothyroidism
 • Sub-clinical Hypothyroidism
 • Recovery from
Recovery from Non-Thyroid ... Thyrotoxicosis • Non-Thyroid ... Thyrotoxicosis • T3 ... Diagnosis #Algorithm #Hypothyroid ... #Hyperthyroid #
Laboratory Evaluation of Patients for Thyroid Disease 
Hyperthyroidism:
 • Graves disease - TSH low; free T4
of Patients for Thyroid ... high; in some cases ... iodine uptake; thyroid ... disease course #hypothyroid ... #hyperthyroid #
Thyroid Disorders - Differential Diagnosis Algorithm
Hypothyroidism:
 • Hasimoto’s
 • Radioactive Iodine 
 • Hypopituitarism
 • Iodine
Thyroid Disorders ... @AmyChung #Thyroid ... Diagnosis #Algorithm #Hypothyroid ... #Hyperthyroid
Thyroid Function Tests (TFTs) and Interpretation

 • TSH, Free T4, Free T3
 • T3 Uptake
 •
Thyroid Function ... Free T4, Free T3 ... • T3 Uptake ... FTI) • Reverse T3 ... @DharSaty #Thyroid
Hyperthyroidism (low TSH, High T4/T3) - Diagnostic Algorithm

Radioactive iodine scan – get if concern for nodular
low TSH, High T4/T3 ... concern for nodular thyroid ... Hyperthyroidism #Hyperthyroid
Hyperthyroidism Overview

Clinical Manifestation of Hyperthyroidism:
 • Fatigue
 • Weight loss
 • Heat intolerance
 • Depression, nervousness
thyrotoxicosis • T3 ... TSH • ↑ Total T3 ... ↑ FT4 and/or ↑ T3 ... : Reduce T4 -> T3 ... hyperthyroidism #causes
Pharmaceutical Management of Hyperthyroidism / Thyroid Storm
Beta-Blockers 
• Decreases sympathetic hyperactivity 
• Partially blocks peripheral conversion
Hyperthyroidism / Thyroid ... conversion of T4 to T3 ... Blocks synthesis of thyroid ... conversion of T4 to T3 ... conversion ofT4 to T3
Algorithm for the diagnostic workup of hyperthyroidism. (T3 = triiodothyronine; T4 = thyroxine; TSH = thyroid-stimulating
(T3 = triiodothyronine ... thyroxine; TSH = thyroid-stimulating