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Thyroid Function Test Interpretation Table

TSH, Free T4, Free T3 and Associated Condition
#Diagnosis #Endocrinology #Hyperthyroid #Hypothyroid #Function
Thyroid Function ... Free T4, Free T3 ... Endocrinology #Hyperthyroid ... #Hypothyroid #Function
Abnormal Serum TSH - Differential Diagnosis Algorithm
Increased TSH
 • Hypothyroidism
 • Sub-clinical Hypothyroidism
 • Recovery from
Recovery from Non-Thyroid ... Thyrotoxicosis • Non-Thyroid ... Thyrotoxicosis • T3 ... Diagnosis #Algorithm #Hypothyroid ... #Hyperthyroid #
Laboratory Evaluation of Patients for Thyroid Disease 
Hyperthyroidism:
 • Graves disease - TSH low; free T4
of Patients for Thyroid ... iodine uptake; thyroid ... procedure that ablates thyroid ... disease course #hypothyroid ... #hyperthyroid #
Thyroid Disorders - Differential Diagnosis Algorithm
Hypothyroidism:
 • Hasimoto’s
 • Radioactive Iodine 
 • Hypopituitarism
 • Iodine
Thyroid Disorders ... @AmyChung #Thyroid ... Diagnosis #Algorithm #Hypothyroid ... #Hyperthyroid
Thyroid Function Tests (TFTs) and Interpretation

 • TSH, Free T4, Free T3
 • T3 Uptake
 •
Thyroid Function ... Free T4, Free T3 ... • T3 Uptake ... FTI) • Reverse T3 ... @DharSaty #Thyroid
Hyperthyroidism (low TSH, High T4/T3) - Diagnostic Algorithm

Radioactive iodine scan – get if concern for nodular
low TSH, High T4/T3 ... concern for nodular thyroid ... Hyperthyroidism #Hyperthyroid
Pharmaceutical Management of Hyperthyroidism / Thyroid Storm
Beta-Blockers 
• Decreases sympathetic hyperactivity 
• Partially blocks peripheral conversion
Hyperthyroidism / Thyroid ... conversion of T4 to T3 ... Blocks synthesis of thyroid ... conversion of T4 to T3 ... conversion ofT4 to T3
Hyperthyroidism Overview

Clinical Manifestation of Hyperthyroidism:
 • Fatigue
 • Weight loss
 • Heat intolerance
 • Depression, nervousness
thyrotoxicosis • T3 ... TSH • ↑ Total T3 ... ↑ Free T4 • Thyroid ... ↑ FT4 and/or ↑ T3 ... : Reduce T4 -> T3
Approach to Thyroid Function Tests in the Evaluation of Hyperthyroidism
 • Low TSH, Low normal T4
Approach to Thyroid ... normal T4 +/- T3 ... TSH, high T4 +/- T3 ... symmetrically enlarged thyroid ... TSH, high T4 +/- T3
Algorithm for the diagnostic workup of hyperthyroidism. (T3 = triiodothyronine; T4 = thyroxine; TSH = thyroid-stimulating
(T3 = triiodothyronine ... thyroxine; TSH = thyroid-stimulating