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diagnosis causes differential endocrinology dermatology pruritus secondary signs systemic dyslipidemia hyperlipidemia hypothyroid interpretation lipidprofiles myopathy pathophysiology primarycare tfts thyroid tsh
Approach to Thyroid Function Tests in the Evaluation of Hyperthyroidism • Low TSH, Low normal T4
T4 → Possibly Central ... Low TSH, high T4 ... +/- T3 → Primary ... TSH, high T4 +/ ... #algorithm #diagnosis
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Pruritus - Generalized ... Differential Diagnosis Algorithm ... /uremia TSH & T4 ... : • Hypothyroidism ... • Hyperthyroidism
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm Blood Glucose: • Diabetes Mellitus Liver Function Tests/Enzymes:
Pruritus - No Primary ... /uremia TSH & T4 ... : • Hypothyroidism ... • Hyperthyroidism ... secondary #systemic #generalized
Hyperthyroidism Overview Clinical Manifestation of Hyperthyroidism: • Fatigue • Weight loss • Heat intolerance • Depression, nervousness
• Insomnia Primary ... goiter • Toxic diffuse ... T3 • ↑ Free T4 ... Glucocorticoids: Reduce T4 ... endocrinology #signs #symptoms
Hypothyroid Myopathy Very common (up to 80% ) in patients with hypothyroidism Pathophysiology: • T4 deficiency leads to
Hypothyroid Myopathy ... patients with hypothyroidism ... Pathophysiology: • T4 ... deficiency leads to abnormal ... pathophysiology #signs #symptoms
Abnormal Lipid Profiles - Differential Diagnosis Algorithm Increased Cholesterol and Triglycerides - Genetic Causes
Abnormal Lipid Profiles ... Differential Diagnosis Algorithm ... Diabetes • Hypothyroidism ... Deficiency • Primary ... Causes • Hypothyroid
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