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diagnosis differential dermatology endocrinology alopecia hairloss pruritus secondary systemic focal hair hashimotos hashitoxicosis hypothyroid interpretation loss pathophysiology primary signs symptoms
Laboratory Evaluation of Patients for Thyroid Disease Hyperthyroidism: • Graves disease - TSH low; free T4
Disease Hyperthyroidism ... high; in some cases ... iodine uptake Hypothyroidism ... disease course #hypothyroid ... #hyperthyroid #
Approach to Thyroid Function Tests in the Evaluation of Hyperthyroidism • Low TSH, Low normal T4
Approach to Thyroid ... Function Tests ... TSH, Low normal T4 ... symmetrically enlarged thyroid ... #algorithm #diagnosis
Hyperthyroidism (low TSH, High T4/T3) - Diagnostic Algorithm Radioactive iodine scan – get if concern for nodular
Hyperthyroidism ... (low TSH, High T4 ... concern for nodular thyroid ... Check pregnancy test ... #Hyperthyroid #
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Pruritus - Generalized ... Systemic and Primary Causes ... Liver Function Tests ... /uremia TSH & T4 ... #causes
Hashitoxicosis ‘Leakage’ symptoms of active Hashimoto’s disease - Hashitoxicosis (Htx) can occur during the initial hyperthyroid stage in
during the initial hyperthyroid ... thyroiditis that causes ... hormone (hyperthyroidism ... enough of it (hypothyroidism ... Diffuse infiltration
Hyperthyroidism Overview Clinical Manifestation of Hyperthyroidism: • Fatigue • Weight loss • Heat intolerance • Depression, nervousness
Hyperthyroidism ... goiter • Toxic diffuse ... T3 • ↑ Free T4 ... Glucocorticoids: Reduce T4 ... #causes #diagnosis
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm Blood Glucose: • Diabetes Mellitus Liver Function Tests/Enzymes:
Liver Function Tests ... /uremia TSH & T4 ... : • Hypothyroidism ... secondary #systemic #generalized ... #causes
Hair Loss (Alopecia) - General (Diffuse and Focal) Differential Diagnosis Algorithm DIFFUSE Scarring - Irreversible-biopsy required • Lupus
Differential Diagnosis Algorithm ... Endocrine • Hypothyroidism ... • Hyperthyroidism ... contraceptives • Hyperthyroid ... #causes
Diffuse Hair Loss (Alopecia) - Differential Diagnosis Algorithm Scarring - Irreversible-biopsy required • Lupus erythematosus • Lichen
Diffuse Hair Loss ... Differential Diagnosis Algorithm ... • Hyperthyroidism ... contraceptives • Hyperthyroid ... #causes
Allopecia - Differential Diagnosis Framework for Hair Loss Localized / Focal Hair Loss Pattern: • Scarring Alopecia:
Traction alopecia Diffuse ... • Endocrine: Hypothyroidism ... disease • Pull test ... Initial Laboratory Tests ... deficiency • Thyroid
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