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diagnosis differential dermatology endocrinology alopecia hairloss generalized pruritus secondary constipation focal geriatrics hair hashimotos hashitoxicosis hypothyroid loss primary signs symptoms
Laboratory Evaluation of Patients for Thyroid Disease Hyperthyroidism: • Graves disease - TSH low; free T4
Disease Hyperthyroidism ... high; in some cases ... iodine uptake Hypothyroidism ... disease course #hypothyroid ... #hyperthyroid #
Hashitoxicosis ‘Leakage’ symptoms of active Hashimoto’s disease - Hashitoxicosis (Htx) can occur during the initial hyperthyroid stage in
during the initial hyperthyroid ... thyroiditis that causes ... hormone (hyperthyroidism ... Diffuse infiltration ... Endocrinology #Diagnosis #Pathophysiology
Hyperthyroidism (low TSH, High T4/T3) - Diagnostic Algorithm Radioactive iodine scan – get if concern for nodular
Hyperthyroidism ... (low TSH, High T4 ... ) - Diagnostic Algorithm ... concern for nodular thyroid ... #Hyperthyroid #
Hyperthyroidism Overview Clinical Manifestation of Hyperthyroidism: • Fatigue • Weight loss • Heat intolerance • Depression, nervousness
Hyperthyroidism ... goiter • Toxic diffuse ... T3 • ↑ Free T4 ... Glucocorticoids: Reduce T4 ... #causes #diagnosis
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Differential Diagnosis Algorithm ... Primary Causes ... /uremia TSH & T4 ... : • Hypothyroidism ... #causes
Hair Loss (Alopecia) - General (Diffuse and Focal) Differential Diagnosis Algorithm DIFFUSE Scarring - Irreversible-biopsy required • Lupus
Differential Diagnosis Algorithm ... Endocrine • Hypothyroidism ... • Hyperthyroidism ... contraceptives • Hyperthyroid ... #causes
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm Blood Glucose: • Diabetes Mellitus Liver Function Tests/Enzymes:
/uremia TSH & T4 ... : • Hypothyroidism ... • Hyperthyroidism ... Pruritus #secondary #systemic ... #causes
Diffuse Hair Loss (Alopecia) - Differential Diagnosis Algorithm Scarring - Irreversible-biopsy required • Lupus erythematosus • Lichen
Diffuse Hair Loss ... Differential Diagnosis Algorithm ... • Hyperthyroidism ... contraceptives • Hyperthyroid ... #causes
Allopecia - Differential Diagnosis Framework for Hair Loss Localized / Focal Hair Loss Pattern: • Scarring Alopecia:
Traction alopecia Diffuse ... • Endocrine: Hypothyroidism ... Scaling, pustules, crusts ... Vitamin D levels Systemic ... deficiency • Thyroid
Pathogenesis of Select Causes of Constipation in Adults and in Elderly • Mechanical (ex. Bowel Obstruction,
Pathogenesis of Select Causes ... Hypothyroidism) ... -> Thyroid hormone ... enteric nervous system ... #constipation #pathophysiology
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