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diagnosis differential endocrinology dermatology alopecia hairloss hypothyroid symptoms generalized pathophysiology pruritus secondary systemic focal hair hashimotos hashitoxicosis hypothyroidism interpretation loss
Approach to Thyroid Function Tests in the Evaluation of Hyperthyroidism • Low TSH, Low normal T4
Approach to Thyroid ... Function Tests ... → Signs of ... symmetrically enlarged thyroid ... #algorithm #diagnosis
Laboratory Evaluation of Patients for Thyroid Disease Hyperthyroidism: • Graves disease - TSH low; free T4
Disease Hyperthyroidism ... high; in some cases ... iodine uptake Hypothyroidism ... disease course #hypothyroid ... #hyperthyroid #
Hyperthyroidism (low TSH, High T4/T3) - Diagnostic Algorithm Radioactive iodine scan – get if concern for nodular
Hyperthyroidism ... (low TSH, High T4 ... ) - Diagnostic Algorithm ... concern for nodular thyroid ... #Hyperthyroid #
Hypothyroidism and Hyperthyroidism - Symptoms and Signs Hypothyroidism: - General - From asymptomatic to myxedema coma, “Like
- Symptoms and Signs ... ophthalmoplegia) • ± Diffuse ... osculating over thyroid ... #Hyperthyroid # ... Symptoms #Signs
Hashitoxicosis ‘Leakage’ symptoms of active Hashimoto’s disease - Hashitoxicosis (Htx) can occur during the initial hyperthyroid stage in
during the initial hyperthyroid ... thyroiditis that causes ... hormone (hyperthyroidism ... enough of it (hypothyroidism ... Diffuse infiltration
Hyperthyroidism Overview Clinical Manifestation of Hyperthyroidism: • Fatigue • Weight loss • Heat intolerance • Depression, nervousness
goiter • Toxic diffuse ... T3 • ↑ Free T4 ... Glucocorticoids: Reduce T4 ... #causes #diagnosis ... endocrinology #signs
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Differential Diagnosis Algorithm ... Systemic and Primary Causes ... Mellitus Liver Function ... /uremia TSH & T4 ... #causes
Hypothyroid Myopathy Very common (up to 80% ) in patients with hypothyroidism Pathophysiology: • T4 deficiency leads to
Hypothyroid Myopathy ... patients with hypothyroidism ... Pathophysiology: • T4 ... impairs musde function ... pathophysiology #signs
Hair Loss (Alopecia) - General (Diffuse and Focal) Differential Diagnosis Algorithm DIFFUSE Scarring - Irreversible-biopsy required • Lupus
Differential Diagnosis Algorithm ... Endocrine • Hypothyroidism ... • Hyperthyroidism ... contraceptives • Hyperthyroid ... #causes
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm Blood Glucose: • Diabetes Mellitus Liver Function Tests/Enzymes:
Mellitus Liver Function ... /uremia TSH & T4 ... : • Hypothyroidism ... • Hyperthyroidism ... #causes
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