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diagnosis hyperkalemia nephrology antiarrhythmics cardiology causes classification differential high pathophysiology comparison effects lactated lr management normal ns phases ringers saline
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Hyperkalemia: • CKD ... transfusion • HTN and edema ... • Recent IV potassium ... Seaweed, Nuts, molasses ... #potassium #high
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Hyperkalemia: • CKD ... transfusion • HTN and edema ... • Recent IV potassium ... Seaweed, Nuts, molasses ... #potassium #high
Antiarrhythmics Pharmacology Summary Cardiac Conduction Phases: Phase 0 - Ventricular Depolarization: • Na+ channels open leading to a
Antiarrhythmics Pharmacology ... to balance out K+ ... Fast Action, ↓ EFR ... 3 - Potassium Channel ... Antiarrhythmics #Pharmacology
Antiarrhythmics - Vaughan Williams Classification: CLASS 1 - Sodium Channel Blockers: • MOA: Block fast Na+ channels
Fast Action, ↓ EFR ... Slow Action, ←→ EFR ... 3 - Potassium Channel ... • MOA: Block K+ ... Vaughan #Williams #Pharmacology
Hyperkalemia - Diagnosis and Management - GrepMed Handbook S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
esp w oliguria / GFR ... Labs: BMP (Assess GFR ... VBG (acidosis), CK ... caution in HTN & edema ... Management #Treatment #potassium
Lactated Ringers (LR) vs Normal Saline (NS) - Comparison Composition of LR: • Sodium 130 mEq/L •
130 mEq/L • Potassium ... trial • Minimal K ... shift • Saline Causes ... • Increases Edema ... NS #comparison #pharmacology
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