28 results
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
hypersensitivity reactions ... Allergen-specific lgE causes ... Acute transfusion reaction ... Tuberculin test, Graft rejection ... allergy #table #classification
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
Transfusion Reactions ... blood donor • Pathophysiology ... without other cause ... transfusion • Pathophysiology ... #Transfusion #Reactions
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Non-Hemolytic Transfusion Reaction ... common immune reaction ... once had another reaction ... Hemolytic Transfusion Reaction ... • Allergic reaction
Hypersensitivity: Definitions
 • Type I - Production of lgE Abs that bind to harmless allergens and
to an allergic reaction ... cell surfaces causes ... an immune reaction ... An allergic reaction ... #Types #Classification
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
common immune reaction ... once had another reaction ... Hemolytic Transfusion Reaction ... Hemolytic Transfusion Reaction ... - Allergic reaction
Anticonvulsants as Mood Stabilizers: Mechanism and Side-effect
Examples: Valproate, Carbamazepine, Lamotrigine
 • Mild anticholinergic effect -> Drowsiness
constipation • Allergic reaction ... mediated cytotoxic reaction ... Systemic effect -> Nausea ... #SideEffects #Pathophysiology
Classification of Jaundice
Unconjugated hyperbilirubinemia (predominantly indirect bilirubin)
 • Increased bilirubin production (eg, hemolytic anemias, hemolytic reactions,
Classification of ... Increased bilirubin production ... anemias, hemolytic reactions ... syndrome, drug reactions ... #differential #causes
Childhood Immunization Schedule: Why we immunize
 • Diphtheria Toxin -> URT inflammation causes pseudomembrane with hardened
URT inflammation causes ... severe swelling causes ... severe swelling causes ... weakness & asymmetric reduction ... peds #pediatrics #pathophysiology
Type IV Hypersensitivity: Pathogenesis and clinical findings
Definition: Unique because it is entirely T-Cell mediated; exposure to
exposure to allergen causes ... Allergic reaction ... Allergy #Immunology #pathophysiology
Angioedema - Classification Diagnosis and Treatment
Types of Angioedema:
 • Acute allergic angioedema - Usually occurs with
Angioedema - Classification ... Non-allergic drug reaction ... cell-mediated in > 90% of cases ... #Angioedema #Classification