34 results
SGLT2 Inhibitors - Pharmacology Summary
Mechanisms of Action: Inhibits SGLT2 (sodium/glucose cotransporter 2) in the proximal tubule,
SGLT2 Inhibitors - Pharmacology ... Weight loss (~2-3kg ... hypovolemia) • GU infections ... (e.g. ... SGLT2 #Inhibitors #Pharmacology
IDSA Recommendations for Treating Visceral and Cutaneous Leishmaniasis in HIV-AIDS
Treating Visceral Leishmaniasis - Preferred Therapy:
 •
., 4 mg/kg on days ... dose of 20–60 mg/kg ... ., 4 mg/kg on days ... opportunistic #infections ... #HIVAIDS #pharmacology
Croup Management - Epinephrine Dosing
Use steroids appropriately, as needed
In older children with mild symptoms, may consider
• Epinephrine MDI ... • Epinephrine MDI ... 7.5 to 15 kg ... IM/SC > 30 kg ... Epinephrine #dosing #pharmacology
Coverage of common antibiotics used in the hospital

For empiric coverage, first define the type of infection,
define the type of infection ... prior resistance. e.g ... #antibiogram #pharmacology
GLP-1 Receptor Agonists - Pharmacology Summary
Mechanisms of Action: Stimulate glucose-dependent insulin release from the pancreas (GLP-1
Receptor Agonists - Pharmacology ... /day or weekly injection ... Victoza) - Daily injection ... side effects (e.g ... Receptor #Agonists #Pharmacology
BEE Syndromes - Non-inflammatory Causes

Immune-mediated conditions affecting the Brain, Eye, and Ear

Visual or auditory symptoms in
Non-inflammatory causes: • Infectious ... • Enteroviral infections ... • Herpes virus infections ... skull neoplasms (e.g ... neuropathy (LHON) plus MRI
IDSA Recommendations for Preventing and Treating Penicillium marneffei Infections in HIV-AIDS
Preventing 1st Episode of Penicilliosis (Primary
Penicillium marneffei Infections ... Treating Acute Infection ... amphotericin B, 3 to 5 mg/kg ... opportunistic #infections ... #HIVAIDS #pharmacology
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
to a preceding infection ... • Most common infection ... Electrodiagnostic studies (Ex EMG ... demyelinating or axonal • MRI ... - Spinal MRI may
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
Vasculitis • Infectious ... Myeloma/amyloid • Infectious ... amiodarone, Alcohol • Infections ... electromyographic (EMG ... ) studies • MRI
Modified penicillin binding proteins as mechanism of resistance to antibiotics.
Penicillin Binding Proteins (Transpeptidases) cross link peptidoglycan
more antibiotic (e.g ... amox for an ear infection ... cephalosporin (e.g ... vancomycin to CTX (e.g ... Proteins #AMR #PBP #pharmacology