15 results
Nephron Pathophysiology - Diuretic Sites of Action
Diuretics
1) Acetazolamide/canagliflozin
2) Osmotic agents (mannitol, urearetics)
3) Loop agents (eg, furosemide)
4)
Nephron Pathophysiology ... ) Loop agents (eg ... Adenosine #Nephron #Pathophysiology ... Action #nephrology #pharmacology
Immune Reactions and Immunosuppressant Drugs

Glucocorticoids - Inhibition of cytokine synthesis, e.g., IL-1, IL-2
Muromonab-CD3 - Monoclonal antibody
Calcineurin
cytokine synthesis, e.g ... Immunosuppressant #Drugs #Pharmacology ... #Pathophysiology
Heparin, Fondaparinux, and Novel Oral Anticoagulants - Pathophysiology

Anticoagulation with parenteral (intravenous or subcutaneous) and oral anticoagulants
Anticoagulants - Pathophysiology ... parenteral agents (e.g ... anticoagulant (e.g ... anticoagulant (e.g ... #Pharmacology #Pathophysiology
Croup Management - Epinephrine Dosing
Use steroids appropriately, as needed
In older children with mild symptoms, may consider
• Epinephrine MDI ... • Epinephrine MDI ... 7.5 to 15 kg ... IM/SC > 30 kg ... Epinephrine #dosing #pharmacology
Fibrinolysis. 
Fibrinolysis occurs when plasminogen is activated to plasmin under the influence of factors such as
anticoagulant drugs (e.g ... Fibrinolysis #Pathway #Pathophysiology ... #Plasminogen #Pharmacology
Benign Prostatic Hyperplasia: Pathogenesis and Medications
Aging
 -> Increased Testosterone -> Testosterone metabolized into DHT by type
alpha-1 blockers (e.g ... -5 inhibitors (e.g ... anticholinergics (e.g ... Hyperplasia #Prostate #Pathophysiology ... #Medications #Pharmacology
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Guillain-Barre Pathophysiology ... Electrodiagnostic studies - EMG ... axonal form • MRI
Iron Deficiency in Congestive Heart Failure (CHF)

Iron deficiency (ID) in heart failure is a common comorbidity
[body weight (kg ... #Failure #CHF #pharmacology ... #pathophysiology
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Electrodiagnostic studies (Ex EMG ... the underlying pathophysiology ... demyelinating or axonal • MRI ... - Spinal MRI may
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
lateral sclerosis Pathophysiology ... EMG: LMN Signs in ... MRI: Brain, cervical