9 results
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation Syndrome ... Classified among the secondary ... Petechial or purpuric rash ... #Diagnosis #Management ... #Hematology #Rheumatology
Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
Algorithm - Approach ... central nervous system ... heart disease, ear ... vesicular rash, ... loss, causing secondary
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
infection risk secondary ... hemolytic anemia) • Systemic ... : • Nephrotic syndrome ... hypogammaglobulinemia #immunology #hematology ... #diagnosis #management
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Systemic disease ... of age • Most common ... Giant retinal tears ... #diagnosis #management ... signs #symptoms #rheumatology
Syphilis - Clinical Manifestations and Treatment

1) Primary Syphilis
 • Direct lesion contact during sex is responsible
treatment. 2) Secondary ... loss • Skin: Rash ... Albuminuria, nephrotic syndrome ... Syphilis #stages #diagnosis ... #management #Treatment
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Drug Associated (Commonly ... Associated: (± 100 % Commonly ... mucositis - Rash ... well as inner ear ... #rheumatology #
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
other diseases • Secondary ... Diagnosis: • Dry ... Nephrogenic DI Hematologic ... Symptomatic: artificial tears ... Diagnosis #Management
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
- Differential Diagnosis ... Vasculitis Differential Diagnosis ... Nodosa: • PAN most commonly ... , mucositis • Rash ... #Rheumatology
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
of the immune system ... STX11, STXBP2 • Secondary ... Acquired) HLH: - Common ... Presentation • Common ... #Management #Hematology