41 results
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
) Pathophysiology ... accumulation of clinical ... Assessment • Clinical ... • Autoimmune diseases ... Nicolas Taar
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... syndrome associated ... age, however the disease ... • Bicytopenia Treatment ... #hematology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
lymphohistiocytosis (HLH ... • HLH Labs: ... Treatment: • Corticosteroids ... #Diagnosis #Management ... #Hematology #Rheumatology
BEE Syndromes - Non-inflammatory Causes

Immune-mediated conditions affecting the Brain, Eye, and Ear

Visual or auditory symptoms in
BEE Syndromes - ... Brain, Eye, and Ear ... and treatment can ... neuropathy (LHON) plus MRI ... lesions and clinical
Gout (Gouty Arthritis) - MSK Radiology
Imaging Findings:
 • Eccentric soft-tissue densities surrounding the third proximal interphalangeal
Gouty Arthritis) - MSK ... - **MSK rads ... diffuse chondral disease ... #diagnosis #msk ... #rheumatology
Hydroxyapatite Deposition Disease (HADD) - MSK Radiology
Imaging Findings:
 • Ovoid hypointense structures along the bursal surface
(HADD) - MSK Radiology ... specificity of tear ... • Treatment for ... #clinical #mri ... #diagnosis #msk
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings
• Primary Sjögren's is a solitary process whereas secondary Sjögren's
Pathogenesis and Clinical ... may be seen in ... - Decreased tear ... #Pathophysiology ... #Diagnosis #Signs
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
common in Asia • HLA-B51 ... association • M > F Clinical ... (Clinical Dx). ... Giant retinal tears ... Arthritis, AS Treatment
Algorithm regarding the diagnosis and treatment of Hereditary Hemochromatosis HH. 

Step 1: In the patient with
and treatment of ... causes of liver disease ... including liver and hematologic ... overload have been ... liver biopsy or MRI
Susac Syndrome - Clinical Triad
 - Central nervous system dysfunction
 - Branch retinal artery occlusion
 -
Clinical Triad ... - Recurrent disease ... flares - 2-year ... arterioles - Treatment ... SusacSyndrome #Triad #Diagnosis