27 results
Approach to Gout
Diagnosis: r/o septic arthritis! Needle-shaped, negative birefringent crystals
Treatment:
 • Weight loss, diet, d/c culprit
Approach to Gout ... Diagnosis: r/o ... 1) 2+ flares/year ... #diagnosis #management ... #rheumatology
Adult-Onset Still's Disease (AOSD)
Rare inflammatory disorder of unknown etiology, difficult to diagnose because of heterogenous presentation.
Must rule out other ... Unclear, but innate immune ... Disease #AOSD #rheumatology ... #diagnosis #management ... #treatment
Susac Syndrome - Clinical Triad
 - Central nervous system dysfunction
 - Branch retinal artery occlusion
 -
Susac Syndrome - ... disease flares - 2-year ... arterioles - Treatment ... SusacSyndrome #Triad #Diagnosis ... #Management #Rheumatology
Gout - Diagnosis and Management Summary

3 Conditions for Gout to Manifest:
1. Hyperuricemia
2. Monosodium urate deposition in
Gout - Diagnosis ... and Management ... sex • Metabolic syndrome ... #diagnosis #management ... #treatment #rheumatology
BEE Syndromes - Non-inflammatory Causes

Immune-mediated conditions affecting the Brain, Eye, and Ear

Visual or auditory symptoms in
Non-inflammatory Causes Immune-mediated ... Brain, Eye, and Ear ... important, as early diagnosis ... and treatment can ... consistent with MS
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
that disrupts immune ... Others: Cellular immune ... Nicolas Taar ... #management #treatment ... #summary #rheumatology
Optic Neuritis - Diagnosis and Management
 • Epidemiology: Female (75%), 18-50 years,
caucasian
 • Symptoms: Moderate visual
Optic Neuritis - Diagnosis ... and Management ... or other auto-immune ... #Management #treatment ... #rheumatology #
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
Immune Reconstitution ... Inflammatory Syndrome ... both • Rule out ... #Inflammatory #Syndrome ... #Management
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
cases/100,000 per year ... Pathophysiology: • Immune ... Guillain-Barre Diagnosis ... #diagnosis #management ... #treatment #neurology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... underlying genetic immune ... • Bicytopenia Treatment ... #management #treatment ... #hematology