10 results
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
, Renal Sodium loss ... can be high or low ... Present (Uosm ≥100): Hypovolemia ... #differential # ... #nephrology
Hyponatremia Differential Diagnosis Algorithm - Utilizing Uric Acid 
ADH promotes Urea/uric acid excretion along with water
Hyponatremia Differential ... Uric Acid - Low ... Uric Acid → SIADH ... #Differential # ... #sodium #low #uricacid
Modified Hyponatremia Algorithm
Hypertonic Hyponatremia: Hyperglycemia, Mannitol, Urologic irrigants
Hypotonic Hyponatremia: 
 • ADH ON (UOsm > 100):
ON (UNa < 30): Hypovolemia ... OFF (UNa > 30): SIADH ... Primary polydipsia, Low ... Algorithm #diagnosis #sodium ... #nephrology
Hyponatremia Diagnosis Algorithm
UOsm ≥ POsm - Vasopressin-Dependent
 • UNa < 20 mEq/L - Appropriate (↓ EABV)
Hyponatremia Diagnosis ... EABV) - Consider: Hypovolemia ... Inappropriate - Consider: SIADH ... Primary polydipsia, Low ... #diagnosis #differential
Hyponatremia - Differential Diagnosis Algorithm
ADH Independent:
 • Tea and Toast Syndrome, Beer Potomania - Low solute
Hyponatremia - Differential ... Independent: • Tea ... Beer Potomania - Low ... insufficiency, SIADH ... #Differential #
Hyponatremia - Differential Diagnosis Algorithm
Hypovolemic - Give volume
Hypervolemic (Edematous) - Look for and treat underlying cause
Hyponatremia - Differential ... Potomania - Tea ... , SSRIs) - SIADH ... #Differential # ... #sodium
Hyponatremia - Differential Algorithm
Isotonic Hyponatremia: Hyperlipidemia, Hyperproteinemia, Recent TURP
Hypotonic Hyponatremia: 
 • Hypovolemia: Diuretics/Nephropathies, Vomiting, Diarrhea,
Hyponatremia - Differential ... : • Hypovolemia ... • Euvolemia: SIADH ... #Differential # ... #sodium #low
Hypernatremia - Differential Diagnosis Workup Algorithm

1) Check Urine Osmolality:
 > 600 mOsm/kg - Implies extrarenal mechanism
Differential Diagnosis ... Workup Algorithm ... • Euvolemic (Low ... #Algorithm #nephrology ... #sodium
Hyponatremia (<135 mEq/L) is a common electrolyte abnormality caused by an excess of total body water
body water in comparison ... osmolality helps to differentiate ... stimulated in states of low ... #RAAS #Hypovolemia ... EBV #potomania #SIADH
Primary Polydipsia
Definition: Excessive volitional water intake
Epidemiology:
 • 6-20% of patients with psychiatric disorders - Most commonly
• Symptomatic hyponatremia ... diabetes insipidus Differential ... Pseudohyponatremia, SIADH ... intoxication Initial Workup ... , Urine Sodium