8 results
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
) - Diagnosis and ... • Immunologic Workup ... life-threatening • Treatment ... Evolution: Chronic disease ... Management #Summary #rheumatology
IgG4-Related Disease
Clinical history:  Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor
4 phenotypes:
 •
IgG4-Related Disease ... supporting long-term ... IgG4 #Related #Disease ... #phenotypes #workup ... #treatment #rheumatology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
• Immunologic Workup ... • Immunologic Workup ... Evolution: Chronic disease ... comparison #table #rheumatology ... #diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
• Autoimmune diseases ... : SLE+++, Adult-onset ... Still disease, ... of emergency, ICU ... #summary #rheumatology
Malignant Hyperthermia Crisis - Guidelines for Crises in Anaesthesia
Unexplained increase in ETCO2 AND tachycardia AND increased
inform theatre team ... ❹ Call for MH treatment ... • Ice packing ... Intraoperative #Checklist #Diagnosis ... #Management #Workup
Peripartum Cardiomyopathy - Summary
1. Definition
 • Towards the end of pregnancy to 5 months postpartum
Differential Diagnosis ... Valvular heart disease ... orthopnea, PND, LE ... Avoid ARBs • ICD ... management #cardiology #treatment
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
non-Hodgkin lymphoma SLL ... cells can indicate disease ... microglobulin Treatment ... #workup #oncology ... #hematology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... Significance (ICUS ... Myeloproliferative Disease ... Workup: • Complete ... Myelodysplastic #Syndromes #diagnosis