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diagnosis pediatrics peds praderwilli signs symptoms syndrome
Prader-Willi Syndrome: Pathogenesis and clinical findings • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Signs/Symptoms/Complications ... Incr Skeletal fractures ... • Short stature ... PraderWilli #Syndrome #genetics ... #pathophysiology
Paget’s Disease: Complications Abnormal Osteoclasts cause excessive bone turnover -> Incr bone resorption, Incr (abnormal) bone formation MSK
Paget’s Disease: Complications ... -> Pathologic fractures ... the vertebral canal ... hearing loss #PagetsDisease ... #pathophysiology
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