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diagnosis growthhormone acromegaly excess feedbackloop management overproduction pituitary signs treatment
Growth Hormone Excess - Pathogenesis and clinical findings • Acromegaly and gigantism share the same pathophysiology
overgrowth: • Carpal ... Tunnel Syndrome ... diagnosis #signs #symptoms ... #endocrinology ... #pathophysiology
Feedback Loop: Growth Hormone (GH) Growth Hormone: • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
lipolysis Signs/Symptoms ... expansion (e.g. carpal ... tunnel, OSA, Incr ... #FeedbackLoop #endocrinology ... #pathophysiology
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook Clinical Presentation: • Classic Acromegaly: frontal
paresthesias (carpal ... tunnel) and OSA ... malignancy Pathophysiology ... Beckwith Wiedemann syndrome ... Diagnosis #Management #Endocrinology
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