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Hepatitis B Management in Cancer

DOI: 10.1200/JCO.20.01757

#HepatitisB #HBV #HepBV #Management #Cancer #oncology #hepatology #algorithm
Hepatitis B Management ... in Cancer DOI: ... JCO.20.01757 #HepatitisB ... #Cancer #oncology ... #hepatology #algorithm
Diagnosis of ascites according to the serum ascites albumin gradient (SAAG)
SAAG ≥ 1.1:
 - Ascitic protein
albumin gradient (SAAG ... ) SAAG ≥ 1.1: ... protein ≤ 2.5 g/dL: Cirrhosis ... albumin #gradient #hepatology ... differential #diagnosis #algorithm
Hepatomegaly - Differential Diagnosis Algorithm
Malignant
 • Primary Carcinoma
 • Metastases
 • Lymphoma
 • Leukemia
 • Polycythemia
Differential Diagnosis Algorithm ... • Budd-Chiari Syndrome ... Primary Biliary Cirrhosis ... Differential #Diagnosis #Algorithm ... #Causes #Hepatology
Causes of Ascites
Normal Peritoneum
Portal hypertension (SAAG > 1.1 g/dL)
  1. Hepatic congestionl
- Budd-Chiari syndrome ... disease - Cirrhosis ... - Alcoholic hepatitis ... - Nephrotic syndrome ... #differential #hepatology
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
HTN: ascites (SAAG ... and hepatorenal syndrome ... • Budd Chiari syndrome ... /acute hepatitis ... Diagnosis #causes #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Differential Diagnosis Algorithm ... • Alcoholic hepatitis ... Infiltrative • Cirrhosis ... • Pancreatic cancer ... Others #LFTs #Hepatology
Serum Ascites Albumin Gradient (SAAG) - Differential Diagnosis
High albumin gradient (>1.1 g/dl):
 - Cirrhosis	
 - Alcoholic
Albumin Gradient (SAAG ... >1.1 g/dl): - Cirrhosis ... - Alcoholic hepatitis ... - Nephrotic syndrome ... Differential #Diagnosis #hepatology
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
• Infectious: Hepatitis ... obstruction, HELLP Syndrome ... Pancreatic Pseudocyst, Cancer ... Causes #Acute #algorithm ... #hepatology
Chronic Hepatitis B - Diagnosis and Management Algorithm

• Who to treat: Essentially treat the pts with
Diagnosis and Management ... Algorithm • ... viremia or have cirrhosis ... #HBV #Algorithm ... #Treatment #Hepatology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
, ↑Tbili/Dbili/AP ... Diagnosis: Viral Hepatitis ... liver transplant center ... Liver #Pregnancy #hepatology ... obgyn #diagnosis #management