25 results
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
predispose to other orthopedic ... Avascular necrosis ... common sites: hip ... , shoulder ... diagnosis #causes #hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Etiology: • Vascular ... Kasabach-Merritt syndrome ... Gardner-Diamond syndrome ... Ig A vasculitis/HSP ... Differential #Diagnosis #hematology
Costoclavicular Maneuver for Thoracic Outlet Syndrome

To perform the Costoclavicular Maneuver, draw the patient's shoulders inferiorly and
Thoracic Outlet Syndrome ... the patient's shoulders ... #Shoulder #PhysicalExam ... #sports #msk #orthopedics ... #vascular
VON-CHOP Mnemonic for Orthopedic Emergencies
V - Vascular compromise (eg ischemic leg)
O - Open fracture
N - Neurological
VON-CHOP Mnemonic for Orthopedic ... Emergencies V - Vascular ... - Compartment syndrome ... H - Hip dislocation ... VONCHOP #mnemonic #Orthopedics
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
Hematological: - HIT ... • Nephrotic Syndrome ... antibodies (APLS should ... pathophysiology #hematology ... differential #diagnosis #vascular
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Vascular Sludging ... Hyperviscosity Syndrome ... HBV infection, HIV ... 20% Sjögren's syndrome ... classification #rheumatology
Orthopedic Emergencies
Compartment Syndrome
 • An increase in compartment pressure to the point where tissue perfusion is
Orthopedic Emergencies ... Compartment Syndrome ... affected part should ... tibia/fibula) and hip ... Hypovolemic Shock #Orthopedics
Hepatopulmonary Syndrome - Diagnosis and Management Summary
A defect in arterial oxygenation due to a gas exchange
Hepatopulmonary Syndrome ... intrapulmonary vascular ... Should be performed ... Intra-pulmonary vascular ... hepatopulmonary #syndrome
Esophageal Necrosis
Etiology:
 - Ischemia and Gastric Outlet Obstruction with GERD may be inciting events
 - Associated
Stevens-Johnson syndrome ... - "Two hit" Hypothesis ... event (low flow vascular ... Necrosis should ... NGT placement should
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
Hyperviscosity, - Vascular ... • TTP, HUS and HIT ... Antiphospholipid syndrome ... Cryofibrinogenemia #diagnosis #rheumatology ... #hematology