21 results
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cold Agglutinin ... younger pts) Differential ... • Diagnostic Test ... Donath-Landsteiner test ... hemolytic #anemia #hematology
Autoimmune Hemolytic Anemia (AIHA) - Differential Diagnosis Table

Warm AIHA (48-70%)
Cold AHA (16-32%)
 • Donath-Landsteiner HA (paroxysmal
Anemia (AIHA) - Differential ... hemoglobinuria) • Cold Agglutinin ... #Anemia #AIHA #Differential ... Diagnosis #Table #hematology
Expected DAT Results in Autoimmune Hemolysis
DAT Negative Hemolysis
 • DAT Poly ( - ), IgG (
( +/- ) Cold agglutinin ... #antiglobulin #test ... Autoimmune #Hemolysis #hematology
Evaluation abnormal liver tests in pregnancy
- Cholestatic Pattern
- Hepatocellular Pattern

#LFTs #transaminits #pregnancy #obgyn #obstetrics #hepatology #diagnosis
abnormal liver tests ... obgyn #obstetrics #hepatology ... #diagnosis #differential
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia - Differential ... Agglutination - Cold agglutinins ... Hemolytic #Anemia #Differential ... Algorithm #workup #hematology
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework
Mild (<100-500): 
 • NAFLD
 • Cirrhosis
 •
Liver Function Tests ... (LFTs) - Differential ... Liver #Function #Tests ... #LFTs #Differential ... #Diagnosis #hepatology
Approach to Thrombotic Microangiopathy (TMA) - Differential Diagnosis and Management Algorithm

Suspected TMA: Unexplained thrombocytopenia + MAHA
Microangiopathy (TMA) - Differential ... Direct antiglobulin test ... Microangiopathy #TMA #Differential ... Management #Algorithm #hematology
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
liver function tests ... abnormal liver blood tests ... of liver blood tests ... Abnormal #Algorithm #Hepatology ... Liver #Enzymes #Differential
Hemolysis - Diagnostic Algorithm and Causes

Increased red cell production: 
 • Increased Reticulocytosis/polychromasia 
 • Erythroid
Anemia #Algorithm #Differential ... Causes #Workup #Hematology ... GrepMed Recommended Text
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
. primary cold agglutin ... Extravascular #Causes #differential ... #diagnosis #hematology