Expected DAT Results in Autoimmune Hemolysis DAT Negative Hemolysis • DAT Poly ( - ), IgG ( - ), C3d ( - ) WAIHA • DAT Poly ( + ), IgG ( + ), C3d ( +/- ) Cold agglutinin disease • DAT Poly ( + ), IgG ( - ), C3d ( + ) Drug-associated • DAT Poly ( +/- ), IgG ( +/- ), C3d ( +/- ) Paroxysmal cold hemoglobinuria • DAT Poly ( + ), IgG ( - ), C3d ( + ) - BWH Medicine Chiefs @BrighamChiefs #direct #antiglobulin #test #DAT #Autoimmune #Hemolysis #hematology #diagnosis
