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cppd differential gout approach calcium degenerative deposition disease druginduced inflammatory jointdisease jointpain myopathies myopathy myositis pain pathophysiology pseudogout pyrophosphate sle
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
Pain - Diagnostic ... spondyloarthropathies, lupus ... #Joint #Pain #MSK ... #rheumatology # ... #differential #diagnosis
Myositis and Myopathies Polymyositis • Progressive, symmetric muscle weakness • Elevated CK, +Anti-Jo, +Anti-Mi2 Dermatomyositis
with temporal arteritis ... Anti-retrovirals, Gemcitabine Lupus ... uncommon 5-15% of lupus ... #differential #diagnosis ... #comparison #rheumatology
Distinguishing between Inflammatory and Degenerative joint disease Inflammatory Joint Disease • Swelling stimulates joint nociceptors -> Pain
in Rheumatoid arthritis ... , Lupus, etc) -> ... #Degenerative #Comparison ... #Versus #MSK #JointDisease ... #JointPain #Diagnosis
CPPD vs Gout == CPPD == Think About CPPD When: • Self-limited synovitis after surgery/trauma (> 65
(shoulders, wrists ... knees, fingers, wrist ... #CPPD #Gout #Comparison ... #rheumatology # ... Diagnosis
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms, Arthritis ... Usual therapeutic management ... #sle #comparison ... #table #rheumatology ... #diagnosis #management
Pseudogout Summary - Calcium Pyrophosphate Deposition Disease (CPPD) Pathophysiology: Pyrophosphate produced by chondrocytes likely precipitates with calcium to
swelling in weird joints ... (shoulders, wrists ... culture used to diagnose ... Deposition #Disease #Rheumatology ... #diagnosis #management
Gout - Diagnosis and Management Summary 3 Conditions for Gout to Manifest: 1. Hyperuricemia 2. Monosodium urate deposition in
and Management ... deposition in joints ... knees, fingers, wrist ... frequent attacks • Arthritis ... #rheumatology
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