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differential joint workup approach disease monoarthritis monoarticular polyarthritis polyarticular algorithm ana antibodies antinuclear aortitis arthropathies arthropathy calcium classification comparison deposition
Aortitis - Differential Diagnosis Framework Non-Infectious Aortitis: • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
- Differential Diagnosis ... Polyarteritis Nodosa (PAN ... Arthritis (RA), ... Systemic lupus ... #rheumatology
Joint Disorders - Differential Diagnosis Algorithm Monoarthritis • Septic • Crystalline - Gout
- Differential Diagnosis ... secondary) • Rheumatoid ... Arthritis (RA) ... should have other symptoms ... Joint #Disorders #msk
CPPD vs Gout == CPPD == Think About CPPD When: • Self-limited synovitis after surgery/trauma (> 65
onset of swelling, pain ... : Resembles RA ... swelling, significant pain ... Gout #Comparison #rheumatology ... #Diagnosis
Pseudogout Summary - Calcium Pyrophosphate Deposition Disease (CPPD) Pathophysiology: Pyrophosphate produced by chondrocytes likely precipitates with calcium to
onset of swelling, pain ... • Resembles RA ... joints ("pseudo-rheumatoid ... with acute neck pain ... Deposition #Disease #Rheumatology
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
rheumaticum • Rheumatic ... gangrenosum • IBD • RA ... lesions • Discoid lupus ... #differential #diagnosis ... #rheumatology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
assay (IFA) is the main ... context of other symptoms ... Arthritis, Sjögren ... ANA #patterns #rheumatology ... #diagnosis #differential
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
Diagnosis Framework ... constitutional symptoms ... Symmetrical: • RA ... #Diagnosis #MSK ... #rheumatology #
Approach to Joint Pain History: Is the pain from: • Joint • Adjacent bursa • Tendon • Ligament • Bone • Muscle • Referred from
or nerve root Symptoms ... in persons with rheumatoid ... arthritis (RA) ... #MSK #rheumatology ... #differential #diagnosis
Rheumatoid arthritis (RA): Pathogenesis and Joint diseases features • RA affects 1% of population, women >
Rheumatoid arthritis ... poly-articular joint pain ... small joints (wrists ... pathophysiology #signs #symptoms ... #diagnosis
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
Approach to Joint Pain ... bacterial), acute rheumatic ... spondyloarthropathies, lupus ... #Joint #Pain #MSK ... #rheumatology #
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