53 results
Sarcoidosis 
Non-caseating granulomas (Composed of T-helper & inflammatory cells) 
Clinical:
 • Disease fatal in 10% of
inflammatory cells) Clinical ... dysrhythmias • Ophthalmologic ... #Sarcoidosis #Diagnosis ... #Symptoms #Signs ... #Pulmonary
Retinoblastoma: Pathogenesis and clinical findings
 • Sporadic mutation -> One allele of RB1 tumor suppressor gene
Pathogenesis and clinical ... Retinoblastoma Signs ... partial retinal red reflex ... pathophysiology #ophthalmology ... #diagnosis #signs
Pott's Disease in Tuberculosis - Diagnosis and Management Summary
Epidemiology:
 - Typically from TB endemic areas
 -
extrapulmonary cases Clinical ... Signs/Symptoms: ... years - May have signs ... symptoms of active pulmonary ... numbness, decreased reflexes
Relative Afferent Pupillary Defect

This maneuver of intermittent light stimulus is called the alternating light test or
alternating light test ... It is a clear sign ... the pupillary reflex ... very sensitive diagnostic ... Defect #Neurology #Clinical
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
Bedside: ice pack test ... /Edrophonium test ... - Cogan sign ... - Peek sign 2. ... #management #neurology
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
Examination: • UMN signs ... Clonus, Babinski’s sign ... • Lhermitte’s sign ... pupillary defect SIGNS ... Signs and symptoms
Leptospirosis
Pathogen: Leptospira (interrogans, kirschneri, noguchii)
Risk Factors:
 • Occupational exposure - Farmers, ranchers, trappers, veterinarians
 • Recreational
failure • Severe pulmonary ... disease ARDS Diagnosis ... Epidemiologic exposure + clinical ... agglutination - test ... #treatment #management
Syncope is a sudden, transient loss of consciousness, which is thought to be secondary to cerebral
causes such as reflex ... further guide management ... orthostatic vital sign ... should be guided by clinical ... The treatment strategy
Fever of Unknown Origin (FUO) - Further Workup

 • CNS symptoms? Get an LP and imaging
Refer to your ‘Fever ... Test for the respective ... thin smear • Signs ... node biopsy • Clinical ... UnknownOrigin #workup #diagnosis
Optic Neuritis - Diagnosis and Management
 • Epidemiology: Female (75%), 18-50 years,
caucasian
 • Symptoms: Moderate visual
Optic Neuritis - Diagnosis ... and Management ... Unilateral • Signs ... #Management #treatment ... #rheumatology #ophthalmology