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Thrombotic Microangiopathies In Systemic Lupus Erythematosus

Dr. Laurent ARNAUD @Lupusreference

#TMAs #Thrombotic #Microangiopathies #Systemic #Lupus #Erythematosus #SLE #hematology
Microangiopathies In Systemic ... Microangiopathies #Systemic ... Erythematosus #SLE #hematology ... #rheumatology # ... differential #diagnosis
Nail Disorders - Primary and Systemic Causes - Differential Diagnosis Algorithm

#NailDisorders #Primary #Secondary #Systemic #dermatology #Differential
- Primary and Systemic ... Causes - Differential ... NailDisorders #Primary #Secondary ... #Systemic #dermatology ... #Differential #
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes
== Primary Skin Lesions ==
Macules /
- Generalized Differential ... Diagnosis Algorithm - Systemic ... Liver Function Tests ... Pruritus #primary #secondary ... #dermatology #Differential
Diagnostic Schema for Hyperferritinemia

Pearl: Diseases associated with extreme elevations: 
1. HLH 
2. Still's disease 
3. Systemic
Systemic histoplasmosis ... Hyperferritinemia #Algorithm #Differential ... #Diagnosis #Hematology
Nail Disorders secondary to Systemic Diseases
Nail Fold Abnormality
 • SLE
 • Scleroderma
 • Dermatomyositis
Koilonychia - Spoon-shaped
Nail Disorders secondary ... to Systemic Diseases ... Grooves • Any systemic ... #Secondary #dermatology ... #Differential #
Causes of Thrombocytosis - Differential Diagnosis
Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis):
 • Acute infection
 • Solid organ
Thrombocytosis - Differential ... Diagnosis Secondary ... Thrombocytosis #Differential ... Diagnosis #Causes #hematology ... #secondary
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm
Reactive:
 - Systemic Inflammatory
     •
Lymphadenopathy - Differential ... Reactive: - Systemic ... Inflammatory • Systemic ... Pancytopenia, WBC differential ... Algorithm #Causes #Hematology
Christmas Tree Rash of Pityriasis rosea
 - small oval scaling patches
 - Christmas tree pattern
 -
palms/soles - Differential ... diagnosis: secondary ... rosea #clinical #dermatology ... #photo #PhysicalExam
Pancytopenia - Differential Diagnosis

Congenital Diseases:
• GATA2 deficiency
• Fanconi’s anemia
• Wiskott-Aldrich syndrome
• Ribosomopathy or telomeropathy

Cancer:
• Leukemia
• Lymphoma

Inflammatory
Pancytopenia - Differential ... Autoimmune Diseases: • Systemic ... #Pancytopenia #Differential ... #Diagnosis #Hematology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Classified among the secondary ... Seen in: • Systemic ... Liver function tests ... Diagnosis #Management #Hematology ... #Rheumatology