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diagnosis neurology classification guillain hematology anemia aplastic cauda caudaequina common cvid dementia equina gbs geriatrics guillainbarre hypogammaglobulinemia immunodeficiency immunology inflammatory
Guillain-Barre Syndrome - Summary Acute AIDP that presents with rapidly progressive flaccid weakness Epidemiology: • 1-2 cases/100,000 per
Guillain-Barre Syndrome ... Pathophysiology: • Immune ... Clinical Features ... • Weakness: Starts ... #management #treatment
Guillain-Barré Syndrome (GBS) Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness Epidemiology: • Incidence: 1
Guillain-Barré Syndrome ... Incidence: 1 to 2 cases ... transplantation CLINICAL ... and sensitive tests ... #management #neurology
Cauda Equina Syndrome Overview Cauda Equina Syndrome: • Prevalence: 1:33,000-100,000 ppl/yr • Incidence: 1.5-3.4 million ppl/yr •
- Emergency Causes ... lumbar stenosis • Vascular ... cord • Guillain-Barre ... #differential # ... diagnosis #causes
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
mutations) • Immune ... Aplastic Anemia Clinical ... and petechiae Causes ... CMV) • Epstein-Barr ... hematology #diagnosis #management
Major neurocognitive disorders (MNCD): Diagnosis and workup 1) Clinical diagnosis Cognitive impairment + loss of autonomy 2)
workup 1) Clinical ... ... laboratory tests ... Aphaso-apraxo-agnosia syndrome ... Frontal atrophy Vascular ... MNCD #Dementia #Differential
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to 8 years Clinical ... (specifically immune ... DDX - Other causes ... infections (Epstein-Barr ... syndrome, HIV)
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Necrotizing, pauci-immune ... respiratory tracts Immune ... tract, and often causes ... retinopathy Lab Tests ... Cryoglobulins • HIV
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
activation of an immune ... Transverse Myelitis - Clinical ... negative, MOG-IgG test ... Myelitis #diagnosis #management ... #neurology #differential
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
Inflammatory Syndrome ... initiation Clinical ... albicans • Epstein Barr ... #Differential # ... Diagnosis #Management
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