49 results
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
myasthenia Diagnosis ... Bedside: ice pack test ... /Edrophonium test ... immunologic assay - MuSK ... #diagnosis #management
Myasthenia Gravis - Summary
 • an autoimmune disease of the postsynaptic neuromuscular junction associated with antibodies
Myasthenia Gravis ... : • Based on clinical ... More likely to cause ... - Improves clinical ... #Myasthenia #Gravis
Causes of Neuromuscular Weakness
 • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Causes of Neuromuscular ... (MS), Epidural ... heavy metals), Critical ... Syndrome, Myasthenia Gravis ... #differential #diagnosis
Leptospirosis
Pathogen: Leptospira (interrogans, kirschneri, noguchii)
Risk Factors:
 • Occupational exposure - Farmers, ranchers, trappers, veterinarians
 • Recreational
non-productive cough, nausea ... ARDS Diagnosis ... Epidemiologic exposure + clinical ... agglutination - test ... #treatment #management
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
• Most common cause ... Lung Abscess Pathophysiology ... Lung Abscess - Clinical ... hemorrhage • Treatment ... #differential #causes
Approach to Thyroid Function Tests in the Evaluation of Hyperthyroidism
 • Low TSH, Low normal T4
Thyroid Function Tests ... Hyperthyroidism: Work-up ... ophthalmopathy → Graves ... ' Disease → Confirm ... Hyperthyroidism #algorithm #diagnosis
Hyperthyroidism Overview

Clinical Manifestation of Hyperthyroidism:
 • Fatigue
 • Weight loss
 • Heat intolerance
 • Depression, nervousness
Hyperthyroidism Overview Clinical ... diffuse goiter (Graves ... ' disease is suspected ... ↑ AST/ALT • Treatment ... hyperthyroidism #causes
IgG4-Related Disease
Clinical history:  Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor
4 phenotypes:
 •
IgG4-Related Disease ... Clinical history ... specific laboratory tests ... IgG4 #Related #Disease ... #phenotypes #workup
Hyponatremia - Diagnosis and Treatment
Hyponatremia is usually caused by the inability to excrete water normally.
Hyponatremia - Diagnosis ... Then, ask 3 questions ... to work through ... vaptans (HF/liver disease ... #Differential #Diagnosis
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... accumulation of clinical ... Assessment • Clinical ... Drugs, Unknown cause ... Treatment: •