34 results
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential Diagnosis ... and Workup History ... (GI symptoms/endemic ... #Causes #Workup ... #hematology
Cold Urticaria
Prevalence - 0.05% in the population
Disease onset - Mostly 2nd to 4th decades of life
Causes
decades of life Causes ... and duration of symptoms ... angioedema Other symptoms ... Cold #Urticaria #diagnosis ... #rheumatology #
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
Pain - Diagnostic ... ), RA, crystal disease ... Like in this case ... #rheumatology # ... approach #workup
Approach to Joint Pain

History:
Is the pain from:
	• Joint
	• Adjacent bursa
	• Tendon
	• Ligament
	• Bone
	• Muscle
	• Referred from
or nerve root Symptoms ... of Joint Disease ... #Pain #MSK #rheumatology ... #approach #workup ... #differential #diagnosis
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
Causes of Bone/Joint ... in Sickle Cell Disease ... predispose to other orthopedic ... #differential #diagnosis ... #causes #hematology
Adrenal Insufficiency - Diagnosis and Management Summary
Primary Adrenal Insufficiency:
Most Common Cause in the US: Autoimmune Adrenalitis
Other
or metastatic disease ... ketoconazole, etomidate) Symptoms ... , infiltrative diseases ... A STIM test can ... ACTH STIM TEST:
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
Rheumatology Workup ... of the affected joint ... (to support a diagnosis ... Arthritis #laboratory #workup ... #diagnosis #testing
Irritable Bowel Syndrome (IBS) - Diagnosis and Workup Summary
Use a positive diagnostic strategy with minimal testing.
and Workup Summary ... last 3 months + symptom ... cultures, but test ... Rule out celiac disease ... Balloon Expulsion Test
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
Multi-system autoimmune disease ... Musculoskeletal: joint ... #diagnosis #signs ... #symptoms #testing ... #workup
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
Diagnosis: ... • A clinical diagnosis ... Rule out other causes ... blockers had the best ... osteoarticular and skin disease