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Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Diagnosis and Management ... Idiosyncratic Drug-induced ... #DILI #Drug #induced ... #gastroenterology ... #hepatology
Heparin Induced Thrombocytopenia (HIT) - Likelihood, Diagnosis and Management
 - HIT Suspected
 - Calculate 4T Score
Heparin Induced ... Diagnosis and Management ... #HIT #Heparin #Induced ... Algorithm #Diagnosis #Management ... #Hematology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Hepatitis (AAH) Drug-Induced ... Hepatitis Procedures Management ... Failure #Cirrhosis #Hepatology ... #gastroenterology ... #management #diagnosis
Management and Complications of Cirrhosis and Ascites

Ascites Workup Algorithm
Ascites Management
Refractory Ascites
Hyponatremia
Spontaneous Bacterial Peritonitis (SBP)
Hepatic Hydrothorax
AKI in
Management and Complications ... Algorithm Ascites Management ... Complications #diagnosis #management ... #gastroenterology ... #hepatology
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework
Mild (<100-500): 
 • NAFLD
 • Cirrhosis
 •
Liver Function Tests ... • DILI (Drug-induced ... Liver #Function #Tests ... Differential #Diagnosis #hepatology
Disorders of the Hepatic and Mesenteric Circulation

Platelets in Cirrhosis
Hypercoagulability in Cirrhosis
Bleeding in Cirrhosis
Portal Vein Thrombosis (PVT)
Mesenteric
Circulation #Disorders #Hepatology ... #Gastroenterology ... #diagnosis #Management
Gastrointestinal Evaluation of Iron Deficiency Anemia
In patients with anemia, diagnose iron deficiency if:
 • Ferritin <
Additional laboratory tests ... chronic kidney tests ... Test for celiac ... change medical management ... workup #diagnosis #gastroenterology
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook

Presentation: 
 • Plts ↓50% (nadir
Heparin Induced ... approach for post-test ... : Confirmatory test ... #HIT #Heparin #Induced ... #Treatment #Hematology
Our approach to the diagnosis and initial management of patients with suspected HIT. Our approach is
diagnosis and initial management ... HIT laboratory tests ... #Diagnosis #Management ... #Hematology #HIT ... #Heparin #Induced
POCUS Stewardship
Right Indication - Right Interpretation -Right Integration
Indication → Pre-test Probability → Spectrum of Disease →
Indication → Pre-test ... Step 2: Pre-test ... Develop a pre-test ... assign a final post-test ... #ultrasound #management