37 results
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
in Sickle Cell Disease ... common sites: hip ... , shoulder ... diagnosis #causes ... #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Platelet Disorders - Differential ... Diagnosis and Workup ... K), H. pylori test ... thyroid function test ... #Workup #hematology
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Clinical triad ... fraction < 20% Differential ... Diaqnoses: • ... Coxsackie, CMV, EBV, HIV ... #treatment #rheumatology
Approach to Joint Pain

History:
Is the pain from:
	• Joint
	• Adjacent bursa
	• Tendon
	• Ligament
	• Bone
	• Muscle
	• Referred from
e.g., congenital hip ... #MSK #rheumatology ... #approach #workup ... #differential # ... diagnosis #arthritis
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
Rheumatology Workup ... should be obtained ... : HIV test, a rubella ... , and low back pain ... ANA and RF (if clinical
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
Clinical features ... Alcohol-induced pain ... : Pain in involved ... #differential # ... hematology
Low Back Pain (Lumbago) - Common Differential Diagnosis and Patterns

Mechanical Low Back Pain:
Aching pain in the
) - Common Differential ... Diagnosis and Patterns ... or inflammatory disease ... Commonly work related ... below the knee,
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
- Arthritis Differential ... Diagnosis Framework ... axial (spine, shoulders ... , hips)? ... #Differential #
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
association • M > F Clinical ... ) Differential Diagnosis ... Arthritis, AS Treatment ... Nonsurgical abdominal pain ... signs #symptoms #rheumatology
IgG4-Related Disease
Clinical history:  Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor
4 phenotypes:
 •
IgG4-Related Disease ... Clinical history ... specific laboratory tests ... #phenotypes #workup ... #treatment #rheumatology