21 results
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
evaluation or workup ... for specific symptoms ... glucocorticoid treatment ... Disorders #Algorithm #Differential ... #diagnosis #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Diagnosis and Workup ... smear, HIV/HCV testing ... K), H. pylori test ... (GI symptoms/endemic ... #hematology
Irritable Bowel Syndrome (IBS) - Diagnosis and Workup Summary
Use a positive diagnostic strategy with minimal testing.
Diagnosis and Workup ... strategy with minimal testing ... last 3 months + symptom ... cultures, but test ... Balloon Expulsion Test
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
elbows/wrists and knees ... thickening Signs and Symptoms ... Scleroderma #SSc #rheumatology ... diagnosis #signs #symptoms ... #testing #workup
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
liver function tests ... suspicious clinical symptoms ... decision for repeat testing ... Abnormal #Algorithm #Hepatology ... Liver #Enzymes #Differential
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Positive Coombs testing ... younger pts) Differential ... • Diagnostic Test ... Donath-Landsteiner test ... hemolytic #anemia #hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
adults in the west ... with no early symptoms ... microglobulin Treatment ... Leukemia #diagnosis #workup ... #oncology #hematology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... Diagnosis: >3 symptoms ... initiation • Differential ... diagnosis #management #hematology ... #oncology
Dysphagia - Differential Diagnosis Framework

Symptom | Diagnosis
• Solid-food dysphagia present for months to years | Mechanical
Dysphagia - Differential ... Diagnosis Framework Symptom ... disorder URGENT WORKUP ... disorder → EGD Treatment ... #Dysphagia #Differential
Algorithm regarding the diagnosis and treatment of Hereditary Hemochromatosis HH. 

Step 1: In the patient with
diagnosis and treatment ... suspected HH based on symptoms ... initial screening test ... elevated, HFE gene testing ... including liver and hematologic