5 results
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
Thrombocytopenia ... (Hemolysis, Elevated ... #AFLP #Obstetrics ... #OBGyn #Hematology ... #Diagnosis #Comparison
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Elevated Liver Enzymes ... • Pregnancy - AFLP ... , HELLP Moderate ... #Hepatology #LiverEnzymes ... #Causes
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
specificity to elevated ... : < 1 • Cirrhosis ... #liver #chemistry ... #diagnosis #differential ... #Hepatology #transaminitis
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
, Elevated Liver ... , Thrombocytopenia ... Disease #Pregnancy #hepatology ... #comparison #differential ... #HELLP #AFLP
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Vascular Causes ... • Pregnancy: HELLP ... specificity to elevated ... : < 1 • Cirrhosis ... #hepatology