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coagulation causes abnormal apixaban aps aptt cascade clot dabigatran dic differential disseminated edoxaban guidelines heparin inhibitor intravascular models pathophysiology pathway
Antiphospholipid Syndrome (APS) APS is a rare autoimmune disorder characterized by recurring blood clots resulting from antibodies
Antiphospholipid ... aPL): • Lupus anticoagulant ... patients to be diagnosed ... Guidelines): • Anticoagulation ... #management #anticoagulation
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
heparin - Other anticoagulants ... inhibitors e.g. antiphospholipid ... inhibitor e.g. antiphospholipid ... Prolonged #Causes #diagnosis ... #differential #hematology
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
thrombin #clot #PT ... #PTT #diagnosis ... #models #hematology ... pathophysiology #anticoagulation ... #anticoagulant
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
• Prolonged PT ... Reduction of pro/anticoagulants ... #Coagulation #diagnosis ... causes #treatment #management ... #hematology
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