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differential hematology aflp algorithm apml causes comparison differentiation disease hellp hepatitis hepatology liver management monoclonal obgyn paraproteinemias postpartum pph pregnancy
Liver Disease in Pregnancy Intrahepatic Cholestasis of Pregnancy (ICP) • Onset/Trimester: 25-32 weeks • Typical clinical features:
of Pregnancy (ICP ... extensive necrosis and hemorrhage ... Liver failure with coagulopathy ... Pregnancy #hepatology #obstetrics ... #differential #diagnosis
Causes of Post-Partum Hemorrhage - Differential Diagnosis Algorithm Blood Loss: >500mL post vaginal delivery OR >1000 mL
of Post-Partum Hemorrhage ... - Differential Diagnosis ... • Pre-existing coagulopathy ... #Differential #Diagnosis ... Algorithm #Causes #Obstetrics
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
if WBC > 5 or elevated ... leukocytosis and coagulopathy ... organ dysfuxtion, ICU ... PCC to reverse coagulopathy ... management #hematology #oncology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
syndrome • Erythema elevatum ... PCH • Evans • ITP ... acquired F-X def (Coagulopathy ... #Differential #Diagnosis ... #Oncology
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