15 results
Low-dose aspirin and low-molecular-weight heparin in lupus and Antiphospholipid Syndrome (APS) pregnancy

• No previous history of
Previous history thrombotic ... APS (arterial or ... history of obstetric APS ... pregnancy #Obstetrics #Anticoagulation ... Aspirin #LWMH #Dosing
Recurrent / Breakthrough DVT During Anticoagulation

Subtherapeutic Anticoagulation
Hypercoagulable State 
 - Antithrombin deficiency 
 - Hypercoagulability ot
Breakthrough DVT During ... Anticoagulation ... Subtherapeutic Anticoagulation ... Hypercoagulability ot Ca ... Behcet's disease - APLS
Comparison of oral anticoagulant agents (DOACS + Warfarin)

Reference: ENLS 2017 Pharmacotherapy. Neurocritical Care Journal.

#DOAC #Dosing #Oral
Comparison of oral ... #DOAC #Dosing #Oral ... #Anticoagulation ... #Comparison #Table
Alteplase (t-PA) for Acute Ischemic Stroke: 
Dosage, Mixing, and Administration Instructions

#TPA #Thrombolytics #Stroke #CVA #Dosage #Dosing
Instructions #TPA #Thrombolytics ... #Stroke #CVA #Dosage ... #Dosing #Mixing
tPA Code Stroke Dosing Chart

Total Dose = 0.9 mg/kg (maximum dose =90 mg)
 - give 10%
tPA Code Stroke Dosing ... give 10% of dose as ... 1 hour #TPA #Dosing ... #Dose #CVA #Thrombolytics
Heparin - Unfractionated Heparin (UFH) vs Low-Molecular-Weight Heparin (LMWH)
UFH:
 • Advantages: 
    -
clearance - Anticoagulation ... administered sub-Q (as ... monitoring Of anticoagulation ... Unknown Optimal dosing ... LMWH #Heparin #comparison
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
During the initiation ... complexes with FVa ... pathophysiology #anticoagulation
Preoperative Risk Evaluation

Major Pre-Op Questions:
1. Does the patient have any modifiable risk factors that could be
components: - CV ... b) CHF c) CVA ... dependent DM ACS ... Anticoagulation ... • <12mo since ACS
Antiplatelet Conversion - Switching Between P2Y12 Inhibitors
Oral P2Y12 inhibitors vary in potency and pharmacokinetic and dynamic
P2Y12 inhibitors during ... syndrome patients (ACS ... inhibition and risk of thrombotic
Differentiating NBTE from Infective Endocarditis
No pathognomonic signs/symptoms or echo features that are specific to NBTE, and
Non-Bacterial Thrombotic ... Autoimmune (SLE/APLS ... #Endocarditis #comparison